![]() Combined with a favorable safety profile, these results may lead to FDA approval of the THN system, and thus a compelling potential new treatment option for patients with OSA. In this trial, Schwartz et al report significant improvements in physiologic measures of OSA and in important patient-reported outcome measures, including daytime sleepiness and quality of life, with THN. ![]() 2, 3 In this issue of JAMA Otolaryngology–Head & Neck Surgery, Schwartz et al 4 report on the safety and effectiveness of the aura6000 THN therapy system (ImThera Medical, San Diego, California) from the THN3 trial, a rigorous international multi-center, parallel-arm, randomized clinical trial. 1 Through parallel development, targeted hypoglossal nerve stimulation (THN), which provides a different approach for activating the tongue muscles, has shown potential as an effective alternative implantable stimulation device for OSA through previous pilot and feasibility studies. ![]() Starting from the preliminary animal studies of the late 1980s, the evolution of our understanding of hypoglossal nerve stimulation culminated in the development of the Inspire II (Inspire Medical Systems, Inc Maple Grove, Minnesota), the first, and currently only, US Food and Drug Administration (FDA)-approved implantable hypoglossal nerve stimulation system to treat OSA. Inserts references/citations from your EndNote Desktop library into your. The best way to create an online backup for your Endnote Library is using the sync function (you can find out more in this subject guide). LibrarySearch, library databases and Google Scholar) to export them into your EndNote Desktop library. Saves your selected references/citations from online resources (e.g. EndNote not only helps you to store and manage your references, it also works with. Use EndNote Online if you: Want a web-based citation management tool Want. This free tool gives you the ability to collect references from print and online resources, organize your reference library, format citations so you can insert them into your research, and create bibliographies. Reflecting the scientific advances of the past several decades, hypoglossal nerve stimulation has emerged as an important tool for the treatment of obstructive sleep apnea (OSA). EndNote Desktop is a software program that: Creates, stores and manages your references/citations. A commonly-used tool at the University of Leeds is EndNote. EndNote Online is a web-based citation management system.
0 Comments
Leave a Reply. |